Technology / separation principle	Silica-membrane technology / chaotropic salt binding
Material	Silica membrane
Format	Spin columns	Low throughput systems, from extra small to extra large scale
	8-well strips	Medium-throughput systems, for vacuum manifolds, centrifuges, and robotic systems
	96-well plates	High-throughput systems, for vacuum manifolds, centrifuges, and robotic systems
Procedure	Principle: binding (high-salt) – washing – elution (low-salt) • Adsorption of DNA / RNA in the presence of chaotropic salts (hydrate shell of DNA / RNA is reversibly removed) • High-salt / ethanolic washing steps to remove contaminants • Low-salt or water elution (hydrate shell is recovered, DNA/RNA is released from the membrane)
Features/Result	Ready-to-use, sequencing and PCR-grade DNA / RNA From extra small to extra large scale, from low to high throughput No alcohol precipitation necessary Fast and easy procedure

*Plasmid DNA Purification*

Plasmid DNA Purification

Plasmid Mini prep	NucleoSpin® Plasmid / Plasmid (NoLid)
	NucleoSpin® Plasmid EasyPure

Manual and automated high throughput (HTP) plasmid Mini prep	NucleoSpin® 8 Plasmid / Core Kit
	NucleoSpin® 96 Plasmid / Core Kit

*Clean-up*

PCR clean-up, gel extraction

Single prep	NucleoSpin® Gel and PCR Clean-up
	NucleoSpin® Gel and PCR Clean-up Midi

Manual and automated high throughput (HTP) PCR clean-up	NucleoSpin® 8 PCR Clean-up / Core Kit
	NucleoSpin® 96 PCR Clean-up / Core Kit

Genomic DNA clean-up

Single prep	NucleoSpin® gDNA Clean-up
	NucleoSpin® gDNA Clean-up XS

RNA

RNA from cells and tissue

Single prep	NucleoSpin® RNA
	NucleoSpin® RNA Plus
	NucleoSpin® RNA XS
	NucleoSpin® RNA Plus XS
	NucleoSpin® RNA Midi

Manual and automated high throughput (HTP)	NucleoSpin® 8 RNA / Core Kit
	NucleoSpin® 96 RNA / Core Kit

MicroRNA

Single prep	NucleoSpin® miRNA
	NucleoSpin® miRNA Plasma

RNA, DNA, and protein

Single prep	NucleoSpin® TriPrep
	NucleoSpin® RNA/Protein
	NucleoSpin® RNA/DNA Buffer Set

RNA from blood

Single prep	NucleoSpin® RNA Blood
	NucleoSpin® RNA Blood Midi

Manual and automated high throughput (HTP)	NucleoSpin® 8 RNA Blood
	N ucleoSpin® 96 RNA Blood

RNA from plant

Single prep	NucleoSpin® RNA Plant and Fungi
	NucleoSpin® RNA Plant

RNA from stool

Single prep	NucleoSpin® RNA Stool

RNA from FFPE samples

Single prep	NucleoSpin® totalRNA FFPE
	NucleoSpin® totalRNA FFPE XS

RNA Clean-up

Single prep	NucleoSpin® RNA Clean-up
	NucleoSpin® RNA Clean-up XS
	NucleoSpin® RNA Clean-up Maxi

Viral RNA and DNA

Viral RNA / DNA from serum and plasma

Single prep	NucleoSpin® Virus
	NucleoSpin® RNA Virus
	NucleoSpin® Dx Virus (CE-IVD marked)
	NucleoSpin® RNA Virus F

Manual and automated high throughput (HTP)	NucleoSpin® 8 Virus / Core Kit
	NucleoSpin® 96 Virus / Core Kit

Viral DNA from serum and plasma

Single prep	NucleoSpin® Blood

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