NucleoSpin Plasma XS
Product informationBenefits
- High recovery even of fragmented DNA > 50 bp
- Elution in as little as 5 μl
- Concentrated DNA even from dilute samples
- DNA ready to use for real-time PCR
| Code | Name | Size | Quantity | Price | |
|---|---|---|---|---|---|
740900.10 |
NucleoSpin Plasma XS |
10 preps | - | Unavailable in your region | |
740900.50 |
NucleoSpin Plasma XS |
50 preps | - | Unavailable in your region | |
740900.250 |
NucleoSpin Plasma XS |
250 preps | - | Unavailable in your region |
Principle
For rapid purification of circulating DNA from plasma and serum
Increased amounts of circulating DNA in plasma have been found in a variety of disorders including cancer, autoimmune diseases, infections, certain fetal diseases, trauma, stroke, and others. Circulating DNA is known to be highly fragmented and low in concentration which creates difficulties in its purification. NucleoSpin® Plasma XS is designed for the isolation of fragmented DNA larger than 50 bp from human EDTA blood plasma. The kit is overcoming the limitations of conventional kits (large membrane diameter associated with large default elution volumes and a resulting DNA concentration which is too low to be directly used as PCR template). NucleoSpin® Plasma XS allows elution in only 5–20 μL, resulting in highly concentrated DNA!
Features
| Technology | Silica-membrane technology |
| Format | XS spin columns - XS design |
| Sample material | 720 µL plasma or serum (multiple loading steps) |
| Fragment size | > 50 bp |
| Typical yield | 0.1-100 ng per ml plasma, depending on sample |
| Typical concentration | 1.2-12000 pg/µl, depending on sample |
| Elution volume | 5-30 µl |
| Preparation time | High sensitivity procedure: 22–27 min/6 preps Rapid procedure: 15–20 min/6 preps |
| Rapid procedure | 15-20 min/6 preps |
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