Principle

For rapid purification of circulating DNA from plasma and serum

Increased amounts of circulating DNA in plasma have been found in a variety of disorders including cancer, autoimmune diseases, infections, certain fetal diseases, trauma, stroke, and others. Circulating DNA is known to be highly fragmented and low in concentration which creates difficulties in its purification. NucleoSpin® Plasma XS is designed for the isolation of fragmented DNA larger than 50 bp from human EDTA blood plasma. The kit is overcoming the limitations of conventional kits (large membrane diameter associated with large default elution volumes and a resulting DNA concentration which is too low to be directly used as PCR template). NucleoSpin® Plasma XS allows elution in only 5–20 μL, resulting in highly concentrated DNA!

Features