LunaGel™ Cold Water Fish Skin – Photocrosslinkable Extracellular Matrix

LunaGel™ harnesses advanced photocrosslinking technology to preserve the bioactivity of natural ECMs, while allowing precise control over matrix porosity and stiffness. This enables the creation of highly tunable, physiologically relevant 3D cell culture environments, ideal for diverse drug discovery, disease modelling, and research applications.

Product Overview

LunaGel™ is a photocrosslinkable extracellular matrix (ECM) designed for highly tunable and biologically relevant 3D cell culture applications. It contains key ECM proteins, including collagen types I, III, IV, and V, as well as connective tissue glycoproteins and proteoglycans, preserving the cell-instructive bioactivity of natural ECMs. LunaGel™ provides an optimal microenvironment for supporting diverse cell types, tissue models, and disease studies.

Features

✔ Ready-to-Use Format

✔ Precise Mechanical Control – Photocrosslinking technology enables tunable stiffness for optimized 3D cell culture conditions.

✔ High Bioactivity – Supports cell attachment, proliferation, and proteolytic degradation, promoting physiologically relevant cell behaviour.

✔ Optically Transparent for Imaging

LunaGel™ forms optically clear hydrogels that remain stable at room temperature, ensuring seamless integration with standard imaging systems and bioassays.

✔ Reliable & Reproducible ECM for 3D Cell Culture

The highly purified gelatin-based LunaGel™ ECM supports the growth and differentiation of viable cells, organoids, and spheroids, providing a consistent and biologically relevant platform for disease modelling, drug screening, and tissue engineering.

Kit Contents

Each kit provides Everything you need for precise, tunable 3D cell culture:

Low Stiffness Kits:

✔ 5 mL LunaGel™ ECM (2x solution, sterile)

✔ 5 vials of freeze-dried photoinitiator (sterile)

High Stiffness Kits:

✔ 5 mL LunaGel™ ECM (1.5x solution, sterile)

✔ 5 vials of freeze-dried photoinitiator (sterile)

How LunaGel™ Photocrosslinkable Extracellular Matrix​ Works

LunaGel™ is supplied as a sterile solution with freeze-dried photoinitiator. Available as Low Stiffness (0 – 6.5 kPa) and High Stiffness kit (0 – 25 kPa). Reconstitute the photoinitiator in PBS, mix with LunaGel™ ECM and cells, and photocrosslink the solution using the Luna Crosslinker™ to form 3D cell culture models. By controlling the duration of light exposure you can produce hydrogels with a specified stiffness. Add your favourite culture media and you’re culturing in 3D!

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