CERO Publications

Below you'll find some publications about the CERO 3D Cell Culture Incubator and Bioreactor

“Bradley Justice, Nadia A.Badr, Robin A.Felder (2009)
3D cell culture opens new dimensions in cell-based assays
Drug Discovery Today 102-107 ”
DOI: 10.1016/j.drudis.2008.11.006

“Susan Breslin, Lorraine O’Driscoll
Three-dimensional cell culture: the missing link in drug discovery
Drug Discovery Today Volume 240-249”
DOI: 10.1016/j.drudis.2012.10.003

“Simone Allazetta, Tanja C. Hausherr, and Matthias P. Lutolf
Microfluidic synthesis of cell-type-specific artificial extracellular matrix hydrogels
Biomacromolecules 2013, 14, 4, 1122–1131”
DOI: 10.1021/bm4000162″

“Maria Mrakovcic, Markus Absenger, Regina Riedl, Claudia Smole, Eva Roblegg, Leopold F Fröhlich, Eleonore Fröhlich
Assessment of long-term effects of nanoparticles in a microcarrier cell culture system
PLoS One. 2013; 8(2);e56791. ”
DOI: 10.1371/journal.pone.0056791

“Zhen-Yu Yang, Jun-Tao Kan, Ze-Yu Cheng, Xian-Li Wang, Yi-Zhun Zhu & Wei Guo
Daphnoretin-induced apoptosis in HeLa cells: a possible mitochondria-dependent pathway
Cytotechnology volume 66, pages51–61(2014)”
DOI: 10.1007/s10616-013-9536-8

“Bernhard Ellinger, Johanna Silber, Anjali Prashar, Johannes Landskron, Jonas Weber, Sarah Rehermann, Franz-Josef Müller, Stephen Smith, Stephen Wrigley, Kjetil Taskén, Philip Gribbon, Antje Labes, and Johannes F. Imhoff
A phenotypic screening approach to identify anticancer compounds derived from marine fungi
Assay Drug Dev Technol. 2014 Apr 1; 12(3): 162–175 ”
DOI: 10.1089/adt.2013.564

“Ching-Yu Lin, Chi-Hui Huang, Yuan-Kun Wu, Nai-Chen Cheng & Jiashing Yu
Maintenance of human adipose derived stem cell (hASC) differentiation capabilities using a 3D culture
Biotechnology Letters volume 36, pages1529–1537(2014) ”
DOI: 10.1007/s10529-014-1500-y

“Simon Wuest, Stéphane Richard, Isabelle Walther, Reinhard Furrer, Roland Anderegg, Jörg Sekler & Marcel Egli
A Novel Microgravity Simulator Applicable for Three-Dimensional Cell Culturing
Microgravity Science and Technology volume 26, pages77–88(2014)”
DOI: 10.1007/s12217-014-9364-2

“Annette Geltmeier, Beate Rinner, Dennis Bade, Katharina Meditz,Reiner Witt, Uwe Bicker, Catrin Bludszuweit-Philipp, Patrick Maier
Characterization of Dynamic Behaviour of MCF7 and MCF10A Cells in Ultrasonic Field Using Modal and Harmonic Analyses
PLOS ONE”
DOI:10.1371/journal.pone.0134999

“Andreas Elanzew, Annika Sommer, Annette Pusch-Klein, Oliver Brüstle and Simone Haupt
A reproducible and versatile system for the dynamic expansion of human pluripotent stem cells in suspension
Biotechnol. J. 2015, 10, 1589–1599”
DOI: 10.1002/biot.201400757

“Akvilė Jarmalavičiūtė, Virginijus Tunaitis, Ugnė Pivoraitė, Algirdas Venalis, Augustas Pivoriūnas
Exosomes from dental pulp stem cells rescue human dopaminergic neurons from 6-hydroxy-dopamine–induced apoptosis
Cytotherapy Volume 17, Issue 7, July 2015, Pages 932-939”
DOI: 10.1016/j.jcyt.2014.07.013

“Aletta Schnitzler, Anjali Verma, Daniel E. Kehoe, Donghui Jing, Julie R. Murrell, Kara A. Der, Manjula Aysola, Peter J. Rapiejko, Sandhya Punreddy, Martha S. Rook
Bioprocessing of human mesenchymal stem/stromal cells for therapeutic use: Current technologies and challenges
Biochemical Engineering Journal Volume 108, 15 April 2016, Pages 3-13”
DOI: 10.1016/j.bej.2015.08.014

“Guoliang Meng, Shiying Liu, Anna Poon, and Derrick E. Rancourt
Optimizing Human Induced Pluripotent Stem Cell Expansion in Stirred-Suspension Culture
Stem Cells and Development Vol. 26, No. 24”
DOI: 10.1089/scd.2017.0090

“Yongxin Zhang, Xianghan Wang, Mao Pong, Liang Chen, Zhijia Ye
Application of Bioreactor in Stem Cell Culture
J. Biomedical Science and Engineering, 2017, Vol. 10, (No. 11), pp; 485-499”
DOI: 10.4236/jbise.2017.1011037

“Michael Gepp, Benjamin Fischer, André Schulz, Johanne Dobringer, Luca Gentile, Julio A. Vásquez, Julia C. Neubauer, Heiko Zimmermann
Bioactive surfaces from seaweed-derived alginates for the cultivation of human stem cells
Journal of Applied Phycology volume 29, pages2451–2461(2017)”
DOI https://doi.org/10.1007/s10811-017-1130-6

“Alina Čebatariūnienė, Akvilė Jarmalavičiūtė, Virginijus Tunaitis, Alina Pūrienė, Algirdas Venalis, Augustas Pivoriūnasa
Microcarrier culture enhances osteogenic potential of human periodontal ligament stromal cells
Journal of Cranio-Maxillofacial Surgery Volume 45, Issue 6, June 2017, Pages 845-854”
DOI: 10.1016/j.jcms.2017.03.009

“Benjamin Fischer, Anna Meier, Annika Dehne, Aseem Salhotra, Thao Anh Tran, Sascha Neumann, Katharina Schmidt, Ina Meiser, Julia C. Neubauer, Heiko Zimmermann, Luca Gentile
A complete workflow for the differentiation and the dissociation of hiPSCderived cardiospheres
Stem Cell Research 32 (2018) 65–72”
DOI: 10.1016/j.scr.2018.08.015

“Róbert Alföldi, József Á. Balog, Nóra Faragó, Miklós Halmai, Edit Kotogány, Patrícia Neuperger, Lajos I. Nagy, Liliána Z. Fehér, Gábor J. Szebeni andLászló G. Puskás
Single Cell Mass Cytometry of Non-Small Cell Lung Cancer Cells Reveals Complexity of In Vivo and Three-Dimensional Models over the Petri-Dish Cells 2019, 8(9), 1093”
DOI: 10.3390/cells8091093

“Alina Čebatariūnienė, Karolina Kriaučiūnaitė, Justina Prunskaitė, Virginijus Tunaitis, and Augustas Pivoriūnas
Extracellular Vesicles Suppress Basal and Lipopolysaccharide-Induced NFκB Activity in Human Periodontal Ligament Stem Cells
Stem Cells Dev. 2019 Aug 1;28(15):1037-1049.”

“Shamsul Sulaiman, Shiplu Roy Chowdhury, Mh Busra Fauzi, Rizal Abdul Rani,Nor Hamdan Mohamad Yahaya, Yasuhiko Tabata, Yosuke Hiraoka, Ruszymah Binti Haji Idrus and Ng Min Hwei
3D Culture of MSCs on a Gelatin Microsphere in a Dynamic Culture System Enhances Chondrogenesis
Int. J. Mol. Sci. 2020, 21(8), 2688”
DOI: 10.3390/ijms21082688

“Emily Fang, Tana Siboonruang, Jonathan Pache, Eugene Reznikov, Reilly Cashmore
Cell Therapy for Spinal Cord Injuries: Design of a Commercial Manufacturing Facility”
https://sites.duke.edu/emilyfang/files/2020/04/FINAL-REPORT.pdf

“Linda Elberskirch , Thorsten Knoll , Rebecca Konigsmark ¨ , Janis Renner, Nadine Wilhelm ,
Hagen von Briesen , Sylvia Wagner
Microfluidic 3D intestine tumor spheroid model for efficient in vitro investigation of nanoparticular formulations
Journal of Drug Delivery Science and Technology 63 (2021) 102496”
DOI: 10.1016/j.jddst.2021.102496

“Eleonore FRÖHLICH, Claudia MEINDL, Maria MRAKOVCIC, Gerd LEITINGER,
Ramona BAUMGARTNER, Eva ROBLEGG
IN-VITRO TESTING FOR IDENTIFICATION OF LONG-TERM EFFECTS OF NANOPARTICLES
Nanocon 2014 in Brno, CZ”

“S Allazetta, L Kolb, S Zerbib, J Bardy, MP Lutolf
Cell-Instructive Microgels with Tailor-Made Physicochemical Properties
small 2015, 11, No. 42, 5647–5656”
DOI: 10.1002/smll.201501001

“Linda Elberskirch, Ronan Le Harzic, Dietrich Scheglmann, Gerhard Wieland, Arno Wiehe, Maria Mathieu-Gaedke, Hartwig R.A. Golf, Hagen von Briesen, Sylvia Wagner
A HET-CAM based vascularized intestine tumor model as a screening platform for nano-formulated photosensitizers
European Journal of Pharmaceutical Sciences 168 (2022) 106046 ”
DOI: 10.1016/j.ejps.2021.106046

“Pascal Baumann, Jürgen Hubbuch
Downstream process development strategies for effective bioprocesses: Trends, progress, and combinatorial approaches
Eng Life Sci. 2017 Nov; 17(11): 1142–1158.”
DOI: 10.1002/elsc.201600033

“Thao Thi Thanh Ngo, Bella Rossbach, Isabelle Sébastien, Julia C. Neubauer, Andreas Kurtz, Krithika Hariharan
Functional differentiation and scalable production of renal proximal tubular epithelial cells from human pluripotent stem cells in a dynamic culture system Cell Prolif. 2022 Mar; 55(3): e13190”
DOI: 10.1111/cpr.13190

“Stange, Katja, Amir Keric, Andreas Friese, and Monika Röntgen.
Preparation of Spheroids from Primary Pig Cells in a Mid-Scale Bioreactor Retaining Their Myogenic Potential
Cells 2022; 11, no. 9: 1453.”
DOI: 10.3390/cells11091453

“Saskia Altmaier, InaMeiser, Emilie Lemesre, Benjamin Chanrion, Rachel Steeg, Lidia Elena Leonte, Bjørn Holst, Boye Schnack Nielsen, Christian Clausen, Katharina Schmidt, Anne Marie Vinggaard, Heiko Zimmermann, Julia Christiane Neubauer, Mikkel AabechRasmussen
Human iPSC-derived hepatocytes in 2D and 3D suspension culture for cryopreservation and in vitro toxicity studies,
Reproductive Toxicology. Volume 111, August 2022, Pages 68-80”
DOI: 10.1016/j.reprotox.2022.05.005

“Chee Keong Kwok, Isabelle Sébastien, Krithika Hariharan, Ina Meiser, Jeanette Wihan, Saskia Altmaier, Isabell Karnatz, Alexander Feile, Alfredo Cabrera-Socorro, Mikkel Rasmussen, Bjørn Holst, Julia C. Neubauer, Christian Clausen, Catherine Verfaillie, Andreas Ebneth, Mattias Hansson, Rachel Steeg, Heiko Zimmermann
Scalable expansion of iPSC and their derivatives across multiple lineages
Reprod Toxicol. 2022 May 17;S0890-6238(22)00068-5.”
DOI: 10.1016/j.reprotox.2022.05.007

“Mathews, M., Wißfeld, J., Flitsch, L.J., Shahraz, A., Semkova, V., Breitkreuz, Y., Neumann, H., Brüstle, O. Reenacting neuroectodermal exposure of hematopoietic progenitors enables scalable production of cryopreservable iPSC-derived human microglia. Stem Cell Rev Rep. 2022 Online ahead of print.”DOI: 10.1007/s12015-022-10433-w