Principle

Purification of genomic, bacterial, and viral DNA from smallest samples

NucleoSpin® Tissue XS is designed for DNA isolation out of Xtra Small samples like microdissected tissue, small blood samples or small amounts of cells. Based on the reliable silica membrane technology NucleoSpin® Tissue XS is overcoming the limitations of conventional kits (large membrane diameter associated with large default elution volumes and a resulting DNA concentration which is too low to be directly used as PCR template) by an innovative column design. A funnel shaped thrust ring is holding a silica membrane of small diameter. It allows the accurate dispensing of small volumes on the membrane and a reduced elution volume of only 5-30 µl. The high DNA yield of NucleoSpin® Tissue XS and the small volume of elution buffer lead to high concentrated DNA, free of impurities and suitable for sensitive downstream applications.

NucleoSpin® Tissue XS is the ideal solution for: microdissected tissue, biopsies (e.g., fine needle aspiration), dried blood spots, buccal swabs, forensic samples, FFPE samples, and other small samples.

	The innovative new thrust ring in a funnel-design allows standard mini prep spin columns to hold a silica membrane of very small diameter. The small diameter of the NucleoSpin® Tissue XS membrane allows efficient elution in only 5–30 μl resulting in highest DNA concentrations ready for all typical downstream applications.

Features