Tapestri single-cell DNA panels and protein panelsProduct information
Untangle the Complexity of Cancer.
Determine the sources of resistance, response, and relapse
Tapestri single-cell DNA panels and protein panels are highly sensitive and customizable panels that enable true multi-omics analysis on the Tapestri Platform from Mission Bio. Whether identifying co-mutation patterns and zygosity in subclones, or cellular identities and subtle cell states, Tapestri single-cell DNA panels and protein panels can be applied across a wide range of discovery and translational research applications.
Tapestri single-cell DNA and protein panels: Trace biomarkers for patient response and relapse
The only comprehensive single-cell DNA platform
Identify SNVs, indels, CNVs, LOH, and translocations from the DNA of thousands of individual cells
The only single-cell DNA and protein platform
Incorporate protein panels and a simple cell-staining protocol to profile genotype and phenotype simultaneously in single cells
Flexibility across analytes and applications
Focus on your regions of interest with targeted content that allows flexibility in experimental design and budget
Custom DNA Panels with Tapestri Designer
With the easy-to-use and intuitive Tapestri Designer software, your custom design can be completed within minutes. Primer design algorithms and multiplex PCR biochemistry have been optimized for the Tapestri Platform so that you can be confident of high design coverage and high panel uniformity. Custom DNA panels can be paired with oligo-conjugated antibodies to enable simultaneous detection of genotype and phenotype from the same cell for true single-cell multi-omics insights.
Clonal evolution is foundational to disease progression in hematologic malignancies, which can impact therapy response, resistance, relapse, and residual disease. Tapestri single-cell hematology panels provide insight into disease drivers and mutation patterns missed during bulk sequencing. By interrogating clonal architecture, rare subclones associated with remission and therapeutic resistance can be identified.
Solid Tumor Panels
Cellular heterogeneity in solid tumor cancers impacts clonal evolution and patient outcomes. Single-cell DNA solid tumor profiling enables high resolution of the genomic diversity in a variety of tumor types by interrogating specific regions in oncogenes and tumor suppressors.
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