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SoftGenetics


SoftGenetics offers software PowerTools for Genetic Analysis

Company Profile

SoftGenetics is the leading provider of effective, biologist friendly, easy-to-use genetic analysis software tools to meet the ever changing needs of today’s genetic researcher and diagnostician. We offer leading edge software powertools for genetic analysis, like Mutation Surveyor® Sequence Analysis and Assembly software, NextGENe® 2nd Generation Sequence Analysis Software, Geneticist Assistant NGS Interpretative Workbench, GeneMarker® the “Biologist Friendly” Genotyping software, JelMarker™ Image Reading and Conversion software, and ChimerMarker™ Automated Chimerism Analysis software. Click on the packages below to read more about the software.

 

Software Packages

Geneticist Assistant™ - Track, review, store, and interpret your NGS data

Developed in collaboration with the Laboratory Medicine, Information Technology and Health Science Research departments of Mayo Clinic Geneticist Assistant NGS Interpretative Workbench, is a web-based tool for the control, visualization, interpretation and historical knowledge base of next generation sequencing data targeted at specific genes for the purpose of identifying potentially pathogenic variants associated with specific conditions such as hereditary colon cancer.

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NextGENe® - the new generation of Sequencing Technologies

NextGENe is the perfect analytical partner for the analysis of desktop sequencing data produced by the ION PGM™, Roche Junior, Illumina MiSeq as well as high throughput systems as the Roche FLX, Applied BioSystems SOLiD™ and Illumina® GA, and HiSeq systems. NextGENe software, which runs on a Windows® Operating System, provides a biologist-friendly point & click interface that does not require scripting or other bioinformatics support.

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MaSTR™ - Enlightened Probabilistic Mixture Analysis Software.

MaSTR software features a rapid and transparent approach to Probabilistic Mixture Analysis which utilizes your forensic acumen in an easy-to-use Windows® environment for research, validation and casework applications. Server based MaSTR software is very cost effective, includes two simultaneous user licenses, and automatic queuing of multiple analyses. More information will be available soon.

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Mutation Surveyor® - Sequence Analysis and Assembly software

Mutation Surveyor® Sequence analysis and assembly software… utilizes our patent pending physical trace comparison technology which provides accuracy >99% when using bi-directional Phred 20 quality sequence traces. The software is an excellent tool for both discovery and diagnostic applications, and accepts sequence traces from all major sequencing systems such as those marketed by Applied BioSystems, Foster City CA, Beckman Coulter or MegaBACE systems, and is compatible with either terminator or primer chemistries.

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GeneMarker® - the “Biologist Friendly” Genotyping software

GeneMarker® is a unique genotype analysis software which integrates new technologies enhancing the speed, accuracy and ease of analysis. Biologist-friendly, the software is an excellent alternative to Applied BioSystems Genotyper® and GeneScan® or GeneMapper®software; LiCor’s SAGA, MegaBACE® Genetic Profiler and Fragment Profiler or MRC Holland’s Coffalyser . Compatible with outputs from all major sequencing systems and simplifies many different applications.

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GeneMarker® MTP - Multi-Template Processor

GeneMarker MTP provides the analysis power of six GeneMarker programs; reducing costs while increasing efficiency of DNA fragment analysis. The automated import and assignment of analysis parameters (templates) is intuitive, reducing complexity and analysis time. GeneMarker MTP maximizes the utility of a CE plate – include up to 6 different chemistries on the same plate. GeneMarker MTP is rapid - processing six 96 well CE plates in approximately 30 seconds.

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GeneMarker® HID - STR Human Identity Software

GeneMarker® HID human identity software is an excellent choice for all forensic profiling applications. This expert system software can be employed as a "biologist-friendly" replacement for GeneScan®/GenoTyper® or as an alternative to GeneMapper® ID and GeneMapper® IDX human identification software, reducing analyst required edits by 18 – 73 % per sample.

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GeneMarker® HTS - Mitochondrial NGS Analysis Software

This Next Generation Sequencing software is exclusively developed for mitochondrial genome analysis for forensic and clinical research applications. The software is compatible with data from high throughput sequencing systems such as Illumina and Ion Torrent.

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ChimerMarker™ - Automated Chimerism Analysis software

ChimerMarker™, automated chimerism analysis software, integrates speed and accuracy with a biologist-friendly interface. The software can be used to monitor chimerism level in both allogeneic and autologous stem cells transplant (SCT) or hematopoietic stem cells transplant (HSCT), bone marrow transplant (BMT, post bone marrow engraftment), and cord and peripheral blood stem cells transplant (PBSCT) samples. The program provides accurate, rapid genotyping and chimerism analysis; automatically identifies donor and recipient peaks in post-BMT samples, calculates percent chimerism and quality metrics for single donor or double donor cases, easily appends for longitudinal monitoring post-BMT, and has multi-lineage capabilities for chimerism analysis of T-cells, B-cells, and other cell type populations

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NextGene Long Read (NextGeneLR)

NextGENeLR can be used for structural variation detection, STR expansion analysis, and whole genome mitochondrial DNA analysis, including low frequency SNV and indel detection, structural variation detection, and mitochondrial haplotyping, with support for mixed samples. Analyses can be set up using an intuitive interface which facilitates batch processing of a number of samples. Recent enhancements to instruments such as PACBIO® and Oxford Nanopore Technologies have improved accuracy to as much as 98%.

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BIOKÉ is the exclusive distributor of SoftGenetics in The Netherlands, Belgium, Luxembourg, Austria, Cyprus, Denmark, France, Estonia, Finland, Germany, Lithuania, Norway, Poland, Portugal, Serbia, Spain, Sweden and Switzerland. Contact us if you have any questions about SoftGenetics products or compatibility.

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